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CHUK — NPY4R
Text-mined interactions from Literome
Liu et al., J Leukoc Biol 2001
(Gout) :
PP1 inhibited crystal induced phosphorylation of ERK1/2 and IkappaBalpha and
suppressed IkappaB kinase (IKK) activation and NF-kappaB binding to the IL-8 promoter, signals that mediate MSU induced IL-8 expression
Mitsuhashi et al., Int J Oncol 2008
:
These results suggest that the
PP1 positively
regulates the TNFalpha induced NF-kappaB pathway at the level of
IKK activation