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AGTR1 — EDN2
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
AGTR1
→
EDN2
(reaction)
Rubio et al., Genomics 1999, Dowal et al., J Biol Chem 2006, Lambert et al., Science signaling 2008, Amatruda et al., Proc Natl Acad Sci U S A 1991, Ferguson et al., J Biol Chem 1986, Chen et al., Biochim Biophys Acta 1996
Text-mined interactions from Literome
Gurantz et al., Circ Res 1999
:
Using quantitative competitive reverse transcription-polymerase chain reaction, we found that norepinephrine,
endothelin , atrial natriuretic peptide, and bradykinin
had no significant effect on
AT(1) mRNA levels
Gu et al., Zhonghua Yi Xue Za Zhi 2002
(Diabetes Complications...) :
[ The
effects of
endothelin blockade on renal expression of
angiotensin II type 1 receptor in diabetic hypertensive rats ]
Roberts et al., Hypertension 2006
:
The purpose of this study was to determine the
role of
angiotensin II type-1 (AT1) receptor activation on
endothelin production induced by serum from pregnant rats exposed to reductions in uterine perfusion
Spinale et al., Circulation 1997
(Disease Models, Animal...) :
ACEI and AT1 Ang II blockade reduced LVEDD ( 4.68+/-0.07 cm ) and increased LVFS ( 25.2+/-0.9 % ) from pacing only ( P < .05 ). Plasma norepinephrine and
endothelin increased by more than fivefold with chronic pacing and remained elevated with AT1 Ang II blockade. Plasma norepinephrine was reduced from pacing-only values by more than twofold in the ACEI group and the combination group. ACEI and
AT1 Ang II receptor blockade
reduced plasma endothelin levels by > 50 % from rapid pacing values
Lerch et al., J Cardiovasc Pharmacol 1998
(Genetic Predisposition to Disease...) :
Effects of
angiotensin II-receptor blockade with losartan on insulin sensitivity, lipid profile, and
endothelin in normotensive offspring of hypertensive parents