Mora et al., Brain Res Bull 1992
:
GLP-1 ( 7-36 ) amide produced an immediate increase ( p less than 0.01 ) of the extracellular levels of glutamine and glutamic acid in the basal ganglia
Tolhurst et al., Endocrinology 2011
:
Asparagine, phenylalanine, and glutamine ( 10 mm ) triggered GLP-1 release from primary cultures, but glutamine was the most efficacious, increasing secretion 1.9-fold with an EC ( 50 ) of 0.19 mm
Rogers et al., J Physiol 2011
(Ion Channel Gating) :
Electrical activity in L-cells was due to large voltage gated sodium currents, inhibition of which by tetrodotoxin reduced both basal and glutamine stimulated GLP-1 secretion
Badole et al., Chem Biol Interact 2013
(Body Weight...) :
Oral l-glutamine increases active GLP-1 ( 7-36 ) amide secretion and improves glycemic control in stretpozotocin-nicotinamide induced diabetic rats