Gene interactions and pathways from curated databases and text-mining

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IL10 — PPARA

Text-mined interactions from Literome

Sacks et al., Diabetes Care 2011 (Coronary Artery Disease...) : Pioglitazone therapy in type 2 diabetes was associated with decreased expression of IL-1ß, IL-1Ra, and IL-10 in EAT ; decreased IL-10 in SAT ; and increased PPAR? in SAT
Borland et al., Cell Signal 2011 : However, these studies demonstrate that stable over-expression of PPARß/d or PPAR? significantly increases the efficacy of ligand activation and represses UVB induced expression of tumor necrosis factor a (TNFa), interleukin 6 (IL6), or IL8 in HaCaT keratinocytes, thereby establishing an excellent model to study the functional role of these receptors in human keratinocytes
Municio et al., Mol Immunol 2011 : Inhibition of PPAR-? activity reduced the production of IL-10 both in the presence and in the absence of AC, but formation of LB in response to zymosan and AC was not observed
Martín et al., J Hypertens 2012 : In addition, pioglitazone increased the interleukin-1ß induced PPAR? mRNA levels