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IL10 — PPARA
Text-mined interactions from Literome
Sacks et al., Diabetes Care 2011
(Coronary Artery Disease...) :
Pioglitazone therapy in type 2 diabetes was associated with decreased expression of IL-1ß, IL-1Ra, and
IL-10 in EAT ; decreased IL-10 in SAT ; and
increased PPAR? in SAT
Borland et al., Cell Signal 2011
:
However, these studies demonstrate that stable over-expression of PPARß/d or
PPAR? significantly increases the efficacy of ligand activation and
represses UVB induced expression of tumor necrosis factor a (TNFa),
interleukin 6 (IL6), or IL8 in HaCaT keratinocytes, thereby establishing an excellent model to study the functional role of these receptors in human keratinocytes
Municio et al., Mol Immunol 2011
:
Inhibition of
PPAR-? activity
reduced the production of
IL-10 both in the presence and in the absence of AC, but formation of LB in response to zymosan and AC was not observed
Martín et al., J Hypertens 2012
:
In addition, pioglitazone increased the
interleukin-1ß induced
PPAR? mRNA levels