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CCND1 — IRS1

Text-mined interactions from Literome

Dalmizrak et al., Cancer Res 2007 (Breast Neoplasms...) : The increased transformed phenotype is characterized by occupancy of the rDNA and cyclin D1 promoters by IRS-1 and the activation of the cyclin D1 , c-myc, and rDNA promoters
Wu et al., Oncogene 2008 : Transcriptional activation of c-myc and cyclin D1 promoters by nuclear IRS-1 does not occur with a mutant, inactive IRS-1 protein ( deletion of the phosphotyrosine binding domain, PTB ) and does not require PI3-kinase activity