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RELA — TMED7
Text-mined interactions from Literome
Chandramohan et al., J Immunol 2004
:
B cell receptor (BCR) engagement of murine WEHI 231 immature B lymphoma cells leads sequentially to a drop in
NF-kappa B and c-Myc, and
induction of the
p27 ( Kip1 ) cyclin dependent kinase inhibitor, which promotes growth arrest and apoptosis
Nasr et al., Oncogene 2005
(Leukemia-Lymphoma, Adult T-Cell...) :
PS-341 treatment of these cells stabilized IkappaBalpha, IkappaBbeta, IkappaBvarepsilon, p21,
p27 and p53 proteins and selectively
inhibited Rel-A DNA binding
NF-kappaB complexes
Lee et al., American journal of physiology. Renal physiology 2008
:
Consequently, the inhibition of Ca ( 2+ ), PKC, EGFR, p44/42 MAPKs, or
NF-kappaB blocked the BSA induced increases in cyclin D1, cyclin dependent kinase (CDK)4, cyclin E, or CDK2 and
restored the BSA induced inhibition of p21 ( WAF/Cip1 ) and
p27 ( Kip1 ) expression
Shankar et al., Molecular cancer 2008
(Neoplasm Metastasis...) :
In xenogrfated tumors, curcumin upregulated the expression of TRAIL-R1/DR4, TRAIL-R2/DR5, Bax, Bak, p21/WAF1, and
p27/KIP1 , and
inhibited the activation of
NFkappaB and its gene products such as cyclin D1, VEGF, uPA, MMP-2, MMP-9, Bcl-2 and Bcl-XL