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MAPK12 — NTF3

Text-mined interactions from Literome

Gottschalk et al., Learn Mem 1999 : Neurotrophin-3 (NT-3) , a close relative of BDNF, did not activate MAPK or PI3K and had no effect on synaptic fatigue in the neonatal hippocampus
Liot et al., Exp Neurol 2004 (MAP Kinase Signaling System) : First, we showed that, in cultured cortical neurons, NT-3 could promote extracellular signal regulated protein kinase/mitogen activated protein kinase ( ERK/MAPK ) and phosphatidylinositol-3' (PI-3) kinase/Akt phosphorylation
Shi et al., Cell Signal 2006 : Dok5 is substrate of TrkB and TrkC receptors and involved in neurotrophin induced MAPK activation
Je et al., J Cell Biol 2006 : Genetic and imaging experiments indicate that the small GTPase Rap1, but not Ras, acts upstream of MAPK activation by NT-3
Lim et al., Biochem Biophys Res Commun 2007 (MAP Kinase Signaling System) : However, the mechanisms by which neurotrophin-3 promotes prolonged Akt/MAPK signaling at an early stage are not well understood
Moubarak et al., J Neurosci 2010 : Altogether, we uncover a new role for FLIP-L as an unexpected critical player in neurotrophin induced mitogen activated protein kinase/ERK- and NF-kappaB mediated control of neurite growth in developing neurons
White et al., Br J Cancer 2010 (Sarcoma, Ewing) : Sustained p38 ( MAPK ) phosphorylation upregulates p75 neurotrophin ( p75 ( NTR ) ) and induces apoptosis in Ewing 's sarcoma family of tumours ( ESFT )
Guiton et al., J Biol Chem 1995 : In cells expressing full-length TrkC, neurotrophin-3 promoted a sustained activation of mitogen activated protein kinase ; TrkC containing kinase inserts only mediated transient activation of mitogen activated protein kinase ... In cells expressing full-length TrkC, neurotrophin-3 promoted a sustained activation of mitogen activated protein kinase ; TrkC containing kinase inserts only mediated transient activation of mitogen activated protein kinase
Cohen et al., J Neurosci 1996 : NGF and NT-3 both induced the phosphorylation of mitogen activated protein kinase ( MAPK ) in OLPs and in OLs
Kumar et al., J Neurosci Res 1998 : Furthermore, NT-3 mediated activation of p21ras and mitogen activated protein kinase ( MAPK ), extracellular signal regulated protein kinase2 ( ERK2 ), were also observed in the progenitor OL cells