Gene interactions and pathways from curated databases and text-mining

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CPP — IRF6

Text-mined interactions from Literome

Moriez et al., Am J Pathol 2005 (Diarrhea...) : In conclusion, LPS mediated effects on CPP include gut inflammation, BT, and visceral hyperalgesia
Moriez et al., Shock 2007 (Endotoxemia) : We aimed to evaluate the role of colonic mucosal mast cells and luminal serine protease activity (PA) in the alterations of CPP and BT induced by LPS ... LPS induced CPP increase and BT were prevented by doxantrazole ... Our data bring evidence of a key role of mucosal mast cells in LPS induced increase of CPP and BT through the release of serine proteases into the colonic lumen