Gene interactions and pathways from curated databases and text-mining

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CYP1A1 — IRF6

Text-mined interactions from Literome

Nicholson et al., Biochem Pharmacol 2001 : The administration of the pro-inflammatory cytokines tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and interferon-gamma (IFN-gamma) directly into the lateral ventricle emulated the effects of LPS on CYP1A activity only in the brain
Gharavi et al., J Pharm Sci 2007 (Carcinoma, Hepatocellular...) : Both TNF-alpha and LPS repressed the beta-naphthoflavone ( betaNF ) -mediated induction of Cyp1a1 and Nqo1 at mRNA and activity levels