◀ Back to EPHB2
EPHB2 — ITGB3
Text-mined interactions from Literome
Das et al., J Biol Chem 2004
(Breast Neoplasms...) :
Furthermore, OPN induces
alpha(v)beta(3) integrin/EGFR mediated
ERK1/2 phosphorylation and AP-1 activation
Brockbank et al., Br J Cancer 2005
(Carcinoma, Squamous Cell...) :
However,
integrin beta1 is not
required for cell growth or activation of FAK and
ERK signalling in vitro or in vivo
Rucci et al., J Cell Sci 2005
(Bone Resorption) :
Engagement of
alphavbeta3 integrin triggered
ERK1/2 phosphorylation, but the underlying molecular mechanism was surprisingly independent of the well known Shc/Ras/Raf-1 cascade, and of phosphorylated MAP/ERK kinase (MEK)1/2, so far the only recognized direct activator of ERK1/2
Pavasant et al., Oral Dis 2008
(MAP Kinase Signaling System) :
The anti-alphavbeta3 integrin antibody could also inhibit ERK activation, suggesting the possible
role of
alphavbeta3 integrin on the regulation of
ERK and cell migration
Park et al., Reproductive biology and endocrinology : RB&E 2009
(Endometrial Neoplasms) :
Thus, in the present study, we further examined the possibility that GnRH
induces integrin beta3 and activation of focal adhesion kinase ( FAK ) through mitogen activated protein kinases ( MAPKs ),
ERK1/2 and p38, to inhibit the growth of HEC1A endometrial cancer cell line