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GCG — IL6

Text-mined interactions from Literome

Yelich et al., Pancreas 1992 : Effects of endotoxin and interleukin-1 on glucagon and insulin secretion from the perfused rat pancreas
Ellingsgaard et al., Proc Natl Acad Sci U S A 2008 : The islet IL-6R is functional, and IL-6 acutely regulates both pro-glucagon mRNA and glucagon secretion in mouse and human islets, with no acute effect on insulin secretion
Stith et al., Circ Shock 1994 : IL-6 produced a transient increase in plasma glucagon that was mirrored by elevated plasma glucose and a depletion of hepatic glycogen
Tsigos et al., J Clin Endocrinol Metab 1997 : In contrast, IL-6 caused significant increases in plasma glucagon levels, which peaked between 120 and 150 min after the IL-6 injection
Pailla et al., JPEN J Parenter Enteral Nutr 1998 : Hepatocyte monolayers were incubated for 6 hours, with either KIC or octanoic acid ( 1 mmol/L ), in the presence of glucagon and TNF-alpha ( 25 micro/L ) IL-6 ( 15 microg/L ) and/or IL-6