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CDH1 — FGF2
Text-mined interactions from Literome
Debiais et al., J Cell Biochem 2001
:
We investigated the
effects of
FGF-2 on cell-cell adhesion and
cadherin expression and the underlying signaling pathways in immortalized human neonatal calvaria ( IHNC ) cells
Ciruna et al., Dev Cell 2001
:
We propose that modulation of cytoplasmic beta-catenin levels, associated with
FGF induced downregulation of
E-cadherin , provides a molecular link between FGF and Wnt signaling pathways at the streak ... We propose that modulation of cytoplasmic beta-catenin levels, associated with
FGF induced downregulation of
E-cadherin , provides a molecular link between FGF and Wnt signaling pathways at the streak
El-Hariry et al., Int J Cancer 2001
(Adenocarcinoma...) :
FGF-1 and
FGF-2 regulate the expression of
E-cadherin and catenins in pancreatic adenocarcinoma
Wu et al., Exp Cell Res 2008
:
But the mRNA or total protein of cadherins had no significant change, suggesting that the
effect of
bFGF on
cadherin expression may work through a post-translational control
Hatanaka et al., PloS one 2012
:
In vitro studies demonstrated that the loss of
FGF signaling
disrupts the
VE-cadherin-catenin complex at adherens junctions by increasing tyrosine phosphorylation levels of VE-cadherin
Lau et al., PloS one 2013
(Neoplasm Invasiveness...) :
The pharmacological inhibition of phosphatidylinositol-3-kinase (PI3K), mammalian target of rapamycin (mTOR), and MEK suggests that both PI3K/Akt/mTOR and MAPK/ERK signaling are required for
FGF2 induced
E-cadherin down-regulation