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MAP2K1 — MAP2K7

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: Complex of MAP2K1-CFLAR-CFLAR-MAP2K1-MAP2K7-MAP2K7-MAP2K7-CFLAR-MAP2K1 (in vivo) Nakajima et al., EMBO J 2006*

Text-mined interactions from Literome

Zhang et al., Arterioscler Thromb Vasc Biol 2005 (Vasculitis) : In contrast, mitogen activated protein kinase kinase-1 ( MEK1 ) inhibition ( dominant negative MEK1 adenovirus or inhibitor U0126 ) suppressed Ang II-induced NF-kappaB promoter activity, NF-kappaB DNA binding activity, p65 phosphorylation, and led to 70 % reduction in IL-6 transcription/production
Shapiro et al., J Biol Chem 1998 : Coexpression of MKK1 or MKK2 with MKP-1 resulted in 7-10-fold activation of mitogen activated protein kinase kinase ( MKK ), which required the presence of regulatory serine phosphorylation sites