Gene interactions and pathways from curated databases and text-mining

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MAP2K1 — PGF

Text-mined interactions from Literome

Yoshida et al., Mol Cell Endocrinol 2005 : Tiludronate attenuated the phosphorylation of both Raf-1 and MEK1/2 induced by PGF2alpha
Hanai et al., Horm Metab Res 2006 : PGF2alpha stimulated phosphorylation of Raf-1, MEK1/2 and p44/p42 MAP kinase were suppressed by minodronate
Mohammed et al., Am J Physiol Lung Cell Mol Physiol 2007 (Mechanotransduction, Cellular) : The stretch induced PlGF production and NO synthesis were attenuated by PD98059, a specific mitogen activated protein kinase kinase-1 and -2 inhibitor
Xu et al., Mol Pharmacol 2008 (MAP Kinase Signaling System) : FP receptor stimulation by PGF ( 2alpha ) induced the phosphorylation of C-Raf, MEK1/2 , and extracellular signal regulated kinases 1 and 2, consistent with the activation of a MAP kinase signaling cascade
Chen et al., Endocrinology 1998 : Additionally, both PGF2alpha ( 1 microM ) and PMA ( 20 nM ) stimulated phosphorylation of Raf-1, MEK1 , and p42mapk in 32P labeled cells