Gene interactions and pathways from curated databases and text-mining

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IRAK4 — NOS2

Text-mined interactions from Literome

Dil et al., Dev Comp Immunol 2003 : Blocking of IL-1 receptor by the anti-IL-1 receptor antibody reduced the LPS mediated iNOS expression by 50 % as quantified by competitive RT-PCR
Yamada et al., Nitric Oxide 2007 : Previously we have reported that the up-regulation of type I IL-1 receptor ( IL-1RI ) is required for the transcriptional activation of iNOS gene, in concert with the activation of transcription factor NF-kappaB
Kwon et al., Biochim Biophys Acta 1996 : The signaling events between IL-1 receptor occupancy and induction of nitric oxide synthase in rat islets involve activation of the transcriptional activator NFkappa B