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CASP3 — IRF5

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: CASP3 → IRF5 (increases, CASP3 Activity)
  Evidence: TABLE V Selected genes up-regulated by IRF-5

Text-mined interactions from Literome

Fantuzzi et al., Eur J Immunol 2001 : In conclusion, IRF-1 regulates IL-18 production and activity mostly by modulating expression of caspase-1 and IL-18BP
Suk et al., J Pharmacol Exp Ther 2003 : Moreover, baicalein inhibited LPS induced nuclear factor-kappaB (NF-kappaB) activity in BV-2 cells without affecting caspase-11 activation, interferon regulatory factor-1 induction , or signal transducer and activator of transcription-1 phosphorylation
Hu et al., J Biol Chem 2009 : IRF-5 is involved in DR signaling upstream of caspase 8, in part because of an IRF-5 dependent increase in caspase 8 activation