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CD86 — CSF2
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Li et al., Scand J Immunol 2000
:
Lipopolysaccharide (LPS) treatment
induced the upregulation of CD40, CD80,
CD86 and the T-cell stimulatory capacity in IL-4-DCs and, to a lesser extent, in the IL-7-DCs whereas
GM-CSF-DCs responded very poorly to such treatment
Zheng et al., J Hematother Stem Cell Res 2000
:
In the
presence of
GM-CSF and IL-4, CB-adherent cells became nonadherent, acquired DC morphology, and showed increased expression of CD1a, CD80,
CD86 , and HLA-DR ; they lost membrane CD14 and some cells with the expression of CD83 and CMRF-44 were generated
Kim et al., Cancer Lett 2001
(Liver Neoplasms, Experimental) :
According to enzyme linked immunosorbent analysis and FACS, we showed that expression of
GM-CSF was increased up to 23-fold in SK-GM and SK-BG cells, and also expression of
B70 was
induced at least 76-97 % in SK-B70 and SK-BG cells ... Expression of
B70 was remarkably
increased by autocrine effect of
GM-CSF in SK-BG cells
Foss et al., Vet Immunol Immunopathol 2003
:
P. pastoris derived
GM-CSF induced expression of antigen presenting ( MHC class II ) and costimulatory (
CD80-CD86 ) molecules and enhanced antigen presenting cell (APC) function consistent with the induction of functional DC
Uchi et al., J Invest Dermatol 2003
:
Exogenous granulocyte-macrophage
colony stimulating factor restored the CX-659S induced inhibition of CD80 and
CD86 expressions of Langerhans cells
Hornell et al., J Immunol 2003
:
GM-CSF also
increases expression of the costimulatory molecules
CD86 and CD40, but not the differentiation marker CD1a or CD16
Liu et al., Allergy 2006
:
The ability of eosinophils to enhance cytokine generation was independent of their source ( blood vs airway ),
activation by
GM-CSF , or detectable expression of human leukocyte antigen ( HLA ) -DR, CD80, or
CD86
Blyszczuk et al., Biochim Biophys Acta 2013
(Autoimmune Diseases...) :
In the
presence of
GM-CSF , inflammatory CD133 progenitors up-regulated integrin, alpha X ( CD11c ), class II major histocompatibility complex, CD80 and
CD86 co-stimulatory molecules reflecting an inflammatory dendritic cell ( DC ) phenotype
Möttönen et al., Br J Rheumatol 1998
(Arthritis, Rheumatoid) :
IL-4 +
GM-CSF , a combination of cytokines known to induce differentiation of dendritic cells,
increased the expression of CD40, CD80 and
CD86 , and decreased the expression of CD14 on SF macrophages