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DDR1 — MAPK3
Text-mined interactions from Literome
Matsuyama et al., J Immunol 2003
(MAP Kinase Signaling System) :
Activation of
DDR1b on differentiated DDR1b overexpressing THP-1 cells or DDR1 on mature DCs
induced the formation of TNFR associated factor 6 (TRAF6)/TGF-beta activated kinase 1 binding protein 1beta/p38alpha
MAPK complex and p38alpha autophosphorylation ... Transfection of differentiated DDR1b overexpressing THP-1 cells with dominant negative TRAF6 completely abrogated DDR1b mediated p38 MAPK phosphorylation, indicating a critical role of TRAF6 in
DDR1b mediated p38
MAPK activation
Matsuyama et al., Am J Respir Cell Mol Biol 2005
(Sarcoidosis, Pulmonary) :
Activation of
DDR1 induced monocyte chemoattractant protein-1 ( MCP-1 ) and matrix metalloproteinase-9 (MMP-9) production in a p38
mitogen activated protein kinase dependent manner from CD14 positive BALF cells of patients with deteriorated sarcoidosis
Ruiz et al., J Biol Chem 2011
(MAP Kinase Signaling System) :
Furthermore, activation of DDR2, JAK2, and ERK1/2
MAPK signaling pathways was
essential for collagen I-induced
DDR1 and matrix metalloproteinase 10 expression