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FASLG — TSC22D3
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Mittelstadt et al., J Biol Chem 2001
:
This could be accounted for by
GILZ mediated inhibition of Egr-2 and Egr-3, NFAT/AP-1-inducible transcription factors that bind a regulatory element in the FasL promoter and up-regulate
FasL expression
Ayroldi et al., Mol Cell Biol 2002
(MAP Kinase Signaling System) :
In fact,
GILZ overexpression
inhibits TCR activated NF-kappaB nuclear translocation, interleukin-2 production,
FasL upregulation, and the consequent activation induced apoptosis