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ANGPT1 — EPHB2

Text-mined interactions from Literome

Harfouche et al., FASEB J 2003 (MAP Kinase Signaling System) : Inhibitors of the PI-3 kinase pathway attenuated Ang-1 induced ERK1/2 phosphorylation at a level up-stream from Raf and MEK1/2, but these inhibitors augmented Ang-1 induced p38 phosphorylation ... We conclude that both anti- ( ERK1/2 ) and pro- ( p38 ) apoptotic members of MAPKs are simultaneously activated by Ang-1 in endothelial cells and that activation of ERK1/2 by Ang-1 is mediated through the PI-3 kinase pathway
Yoon et al., Biochem Biophys Res Commun 2003 : Localization of Tie2 and phospholipase D in endothelial caveolae is involved in angiopoietin-1 induced MEK/ERK phosphorylation and migration in endothelial cells
Smith et al., Endocrinology 2006 (MAP Kinase Signaling System) : Stimulation of Ishikawa cells and human endometrial biopsy explants with 100 nm iloprost ( a PGI analog ) rapidly activated ERK1/2 signaling and induced the expression of proangiogenic genes, basic fibroblast growth factor, angiopoietin-1 , and angiopoietin-2, in an epidermal growth factor receptor (EGFR) dependent manner
Harfouche et al., Am J Physiol Heart Circ Physiol 2006 : When vascular endothelial growth factor ( VEGF ) was present along with Ang-2, ERK1/2 phosphorylation was inhibited, whereas augmentation of Ang-1 induced ERK1/2 phosphorylation was triggered by VEGF