Gene interactions and pathways from curated databases and text-mining
IL8: top 25 interacting genes
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only IL8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with IL8, not among the Top 25
Other genes interacting with IL8. Mouse-over to show number of abstracts or databases. Sorted by article count (sort alphabetically).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

TLR4 ▸ TLR2 ▸ FOS ▸ IL4 ▸ IL2 ▸ CSF2 ▸ IL17A ▸
ICAM1 ▸ TLR3 ▸ NM ▸ TLR5 ▸ PTGS2 ▸ CD40 ▸ IL13 ▸
AHSA1 ▸ VEGFA ▸ TLR9 ▸ TLR1 ▸ CA2 ▸ CCL2 ▸ TLR8 ▸
IL3 ▸ TLR7 ▸ IL15 ▸ TLR6 ▸ RNF19A ▸ TGFB1 ▸ LTA ▸
TLR10 ▸ IL33 ▸ IL5 ▸ TCF21 ▸ IL18 ▸ TCF4 ▸ F2RL1 ▸
NOS2 ▸ CRK ▸ IL22 ▸ TCF20 ▸ TCF15 ▸ TCF19 ▸ TCF12 ▸
TCF23 ▸ TCF25 ▸ TCF7 ▸ TCF3 ▸ TCF24 ▸ PIK3CA ▸ NA ▸
PIK3R1 ▸ CSE ▸ NFKBIA ▸ IL1RN ▸ LPA ▸ IL32 ▸ MMP9 ▸
CDC73 ▸ HGF ▸ GRAP2 ▸ CTR9 ▸ APOB ▸ WDR61 ▸ EGF ▸
PAF1 ▸ LEO1 ▸ IL31 ▸ MMP2 ▸ S100A8 ▸ IFNB1 ▸ CXCR1 ▸
IL7 ▸ IL11 ▸ FGF2 ▸ ITGAM ▸ IL9 ▸ IL20 ▸ IL25 ▸
IL19 ▸ IL21 ▸ IL16 ▸ IL24 ▸ IL37 ▸ MMP3 ▸ SAA1 ▸
INS ▸ IL27 ▸ IL26 ▸ POLDIP2 ▸ FAS ▸ IL34 ▸ EGFR ▸
MIF ▸ NOS1 ▸ PI3 ▸ CXCR2 ▸ AKT3 ▸ AKT1 ▸ ALB ▸
CRP ▸ AKT2 ▸ MMP13 ▸ NOX1 ▸ IKBKB ▸ CD14 ▸ CALM3 ▸
CASP3 ▸ MMP1 ▸ CASP4 ▸ CASP12 ▸ CASP14 ▸ CASP6 ▸ CASP2 ▸
CASP10 ▸ CASP16 ▸ CASP5 ▸ CASP1 ▸ CASP7 ▸ F2R ▸ NOX4 ▸
CD40LG ▸ CASP8 ▸ NOS3 ▸ CASP9 ▸ NOX5 ▸ HMGB1 ▸ PLG ▸
NOX3 ▸ PTX3 ▸ MYLIP ▸ TGFB2 ▸ SELE ▸ CHUK ▸ LIF ▸
NOD1 ▸ PTK7 ▸ PTK2 ▸ ITGB2 ▸ TNFSF10 ▸ PTK6 ▸ MYD88 ▸
IGF1 ▸ MAP3K7 ▸ SRC ▸ CXCL12 ▸ MMP8 ▸ PRG3 ▸ PTX4 ▸
IL12B ▸ STAT3 ▸ IFNA2 ▸ LEP ▸ PRG4 ▸ MUC1 ▸ ERVK-6 ▸
GP9 ▸ GP5 ▸ GP6 ▸ GP2 ▸ PRG2 ▸ TREM1 ▸ IKBKG ▸
VIP ▸ IFNA1 ▸ SOD3 ▸ MMP14 ▸ IFNA10 ▸ PRKAR1B ▸ IFNA16 ▸
HNRNPH1 ▸ PRKACB ▸ PRKACG ▸ HNRNPF ▸ IFNA17 ▸ PTBP2 ▸ CSF3 ▸
VCAM1 ▸ IFNA6 ▸ IFNA13 ▸ HDAC2 ▸ PRKAR2B ▸ SOD1 ▸ PTBP1 ▸
IFNA7 ▸ CRH ▸ IFNA5 ▸ IFNA14 ▸ MMP7 ▸ WNK1 ▸ PAM ▸
IFNA4 ▸ IFNA8 ▸ IFNA21 ▸ IL12A ▸ MPO ▸ PRKAR2A ▸ PLD2 ▸
PRKAR1A ▸ LTB ▸ SERPINE1 ▸ SOD2 ▸ S100A12 ▸ MMP20 ▸ MMP11 ▸
MMP27 ▸ TGFB3 ▸ EDN1 ▸ MMP28 ▸ CCL3 ▸ MSH3 ▸ SETD2 ▸
MMP15 ▸ MMP25 ▸ MMP10 ▸ TNFRSF1A ▸ ELANE ▸ HDAC1 ▸ MMP12 ▸
NOD2 ▸ CXCL10 ▸ MMP26 ▸ IL1R1 ▸ CSK ▸ SPP1 ▸ FGF1 ▸
PLD1 ▸ CAT ▸ EGR1 ▸ MMP16 ▸ MMP19 ▸ MMP24 ▸ MMP21 ▸
MMP17 ▸ ANGPT2 ▸ MSH4 ▸ QRICH2 ▸ PLD6 ▸ TAB1 ▸ FGF7 ▸
SYT1 ▸ NAALADL1 ▸ TRAF6 ▸ MSH5 ▸ MAP2K1 ▸ MSH6 ▸ QRICH1 ▸
PLD5 ▸ MSH2 ▸ PLD3 ▸ PLA2G1B ▸ SST ▸ CD8A ▸ PLD4 ▸
CD4 ▸ AHR ▸ FASLG ▸ FGF3 ▸ HMOX1 ▸ FGF13 ▸ ETS1 ▸
STAT1 ▸ SELP ▸ FGF4 ▸ HDAC3 ▸ FGF22 ▸ FGF19 ▸ CD28 ▸
HDAC5 ▸ FGF20 ▸ FGF17 ▸ CXCL1 ▸ C1QB ▸ RAC1 ▸ FGF6 ▸
FGF5 ▸ CD38 ▸ SAA2 ▸ SOCS3 ▸ FGF14 ▸ FGF8 ▸ CSRP1 ▸
FGF11 ▸ P2RY6 ▸ TNFSF12 ▸ SELL ▸ HSPD1 ▸ ADIPOQ ▸ FGF9 ▸
CD46 ▸ FGF12 ▸ FGF18 ▸ FGF21 ▸ ITGB1 ▸ TXN ▸ FGF10 ▸
LTF ▸ NGF ▸ FGF16 ▸ FGF23 ▸ CSF1 ▸ PPARG ▸ PDLIM7 ▸
HDAC6 ▸ C1QA ▸ STX2 ▸ PDGFB ▸ BCL3 ▸ CD79A ▸ HDAC4 ▸
MUC21 ▸ MUC16 ▸ MTX1 ▸ PDCD11 ▸ RHOA ▸ PLAU ▸ HDAC9 ▸
SETBP1 ▸ RBBP4 ▸ HDAC8 ▸ ANGPT1 ▸ MUC13 ▸ MUC15 ▸ CPOX ▸
MUC17 ▸ MUC12 ▸ CD8B ▸ PPARA ▸ PRTN3 ▸ ANG ▸ CFTR ▸
APC ▸ ECM1 ▸ CISH ▸ ECM2 ▸ HDAC11 ▸ MUC6 ▸ MUC4 ▸
HSPG2 ▸ RHO ▸ GPI ▸ ST8SIA2 ▸ MTOR ▸ CXCR4 ▸ NPS ▸
MUC2 ▸ PRKCD ▸ PLA2G4A ▸ TNMD ▸ MUC22 ▸ HDAC10 ▸ STAT4 ▸
IL2RA ▸ HES1 ▸ CXCR3 ▸ ITIH4 ▸ RBBP7 ▸ HDAC7 ▸ AGTR2 ▸
MUC8 ▸ PF4 ▸ NAP1L4 ▸ HSPB1 ▸ MUC19 ▸ CR1 ▸ MUC7 ▸
STX1A ▸ TNFSF13B ▸ SAA4 ▸ TRPV1 ▸ TAT ▸ MUC20 ▸ LPL ▸
IRAK3 ▸ PRR11 ▸ TF ▸ IFI44 ▸ EPO ▸ PRKAB1 ▸ PRKCA ▸
TAC1 ▸ RENBP ▸ DDIT3 ▸ UTP15 ▸ CALM2 ▸ AZU1 ▸ PRDX2 ▸
PAEP ▸ IRAK1 ▸ ICAM3 ▸ PRKAB2 ▸ BCL10 ▸ SMAD3 ▸ CYP1A1 ▸
IBD7 ▸ PRR19 ▸ HES3 ▸ ADAM11 ▸ HES6 ▸ CALM1 ▸ JAK2 ▸
ARG1 ▸ UTP23 ▸ PGD ▸ CCL20 ▸ PRR5 ▸ FGG ▸ PRR26 ▸
IBD5 ▸ MT4 ▸ PRR16 ▸ ETS2 ▸ PRR15 ▸ PRL ▸ EMD ▸
CXCL17 ▸ PGF ▸ IBD2 ▸ A2M ▸ ARG2 ▸ TPO ▸ CTNNB1 ▸
PRR18 ▸ ESR1 ▸ HES5 ▸ IBD4 ▸ NTS ▸ IBD3 ▸ ICAM4 ▸
PRKAG1 ▸ OSM ▸ MUC5AC ▸ NR0B1 ▸ IBD6 ▸ PRKAG2 ▸ PKD1 ▸
RNASE3 ▸ IBD8 ▸ FCGR1A ▸ PTAFR ▸ PRR12 ▸ FGA ▸ MAP2K7 ▸
FOXO3 ▸ ELF3 ▸ UTP20 ▸ UTP18 ▸ ROCK2 ▸ APEX1 ▸ PRKAA1 ▸
NR4A2 ▸ CXCL11 ▸ ELF4 ▸ PRR24 ▸ TGFA ▸ IL17F ▸ PRR13 ▸
PRKAA2 ▸ DUSP1 ▸ BCL2 ▸ SELPLG ▸ SEA ▸ MT3 ▸ ADCYAP1 ▸
HES2 ▸ NUP43 ▸ PRR4 ▸ HES7 ▸ TAC4 ▸ PRR14 ▸ UTP6 ▸
TAC3 ▸ SIGLEC7 ▸ PRR21 ▸ ADAM17 ▸ IBD9 ▸ PRR7 ▸ PRR9 ▸
TFPI ▸ ICAM5 ▸ HDC ▸ MPL ▸ GRP ▸ TP53 ▸ ICAM2 ▸
CCR5 ▸ ICOSLG ▸ UTP3 ▸ PRR3 ▸ IL1R2 ▸ MAP3K1 ▸ DEFA1 ▸
MET ▸ BRAF ▸ PRR22 ▸ CHI3L1 ▸ CXCL9 ▸ HBEGF ▸ PRR25 ▸
RELB ▸ CXCL6 ▸ HES4 ▸ SERPINE2 ▸ APOA1 ▸ MYO6 ▸ CEACAM6 ▸
HCG14 ▸ NPY4R ▸ RETN ▸ FOSL1 ▸ CAPN3 ▸ FUT3 ▸ MTA3 ▸
DNASE1 ▸ WNT4 ▸ TEC ▸ IDO1 ▸ CYP19A1 ▸ PTHLH ▸ CAPN2 ▸
IGF2 ▸ CAPN6 ▸ MAP2K2 ▸ CDC42 ▸ CEACAM1 ▸ RABEPK ▸ PARK7 ▸
TPT1 ▸ CD69 ▸ KRT10 ▸ HRH1 ▸ MPG ▸ CD2 ▸ HMGB4 ▸
WNT16 ▸ WNT3 ▸ KDR ▸ HMGB3 ▸ HCG20 ▸ CD44 ▸ F7 ▸
ADM ▸ GHRH ▸ APOE ▸ ITGA5 ▸ ANPEP ▸ CNR1 ▸ CDH5 ▸
HCG16 ▸ F10 ▸ C1orf228 ▸ CEBPA ▸ CXCL13 ▸ CD1D ▸ IL23A ▸
OXA1L ▸ PAK1 ▸ FUT4 ▸ GSTM1 ▸ GRB7 ▸ MAPKAPK2 ▸ SOAT1 ▸
DEFA1B ▸ PROK1 ▸ GAL ▸ RAC3 ▸ FUT5 ▸ CTSS ▸ CXCL2 ▸
PDGFA ▸ IFIH1 ▸ ABL1 ▸ GRB10 ▸ ALX3 ▸ HBD ▸ TNFRSF9 ▸
DPM2 ▸ SYK ▸ MAP2K4 ▸ BPI ▸ CSH1 ▸ MKNK1 ▸ HCG27 ▸
MTA1 ▸ FGFR2 ▸ PGP ▸ ELF2 ▸ HCG26 ▸ CAPN12 ▸ MAP2K6 ▸
NAMPT ▸ WNT11 ▸ MTA2 ▸ HCG18 ▸ IRS1 ▸ FOXP3 ▸ PINK1 ▸
DPM1 ▸ SMAD6 ▸ SMAD7 ▸ TMSB4X ▸ AGTR1 ▸ RAC2 ▸ HCG9 ▸
SMAD9 ▸ GAST ▸ GRB2 ▸ CD83 ▸ WNT1 ▸ CAPN7 ▸ BLM ▸
HCG22 ▸ DUOX1 ▸ FUT9 ▸ HRAS ▸ KSR2 ▸ KLK3 ▸ ROCK1 ▸
AREG ▸ CCL4 ▸ FUT2 ▸ SMAD2 ▸ RAG1 ▸ ALX4 ▸ AR ▸
BCR ▸ FCER2 ▸ FUT6 ▸ CSTA ▸ PAH ▸ CAPN9 ▸ BMP2 ▸
CXCL14 ▸ MEPE ▸ NLRP3 ▸ HIF1A ▸ JAK3 ▸ PAK3 ▸ TBP ▸
FGB ▸ CX3CL1 ▸ PAK2 ▸ CGN ▸ ALX1 ▸ ELF5 ▸ REL ▸
CAPN10 ▸ FMR1 ▸ S100A9 ▸ CAPN8 ▸ CNR2 ▸ CA1 ▸ MBP ▸
TRNAI1 ▸ TNFSF11 ▸ HMGB2 ▸ SMAD5 ▸ CXCL16 ▸ PARK2 ▸ STAT5A ▸
RNASE2 ▸ CDH1 ▸ ELAVL1 ▸ NR4A1 ▸ SCARB1 ▸ VCP ▸ CEBPB ▸
ELF1 ▸ GRPR ▸ HCG4 ▸ GIP ▸ FUT10 ▸ CAPN13 ▸ PAK4 ▸
TACR1 ▸ ASIP ▸ WNT6 ▸ FUT7 ▸ FOXO1 ▸ MYO10 ▸ LBP ▸
PTGS1 ▸ CD86 ▸ SMAD4 ▸ DPM3 ▸ KLRB1 ▸ HLA-DRB1 ▸ FXYD1 ▸
SERPINB2 ▸ PAK6 ▸ MAP2K3 ▸ PTPN11 ▸ HCG17 ▸ TNPO1 ▸ SPESP1 ▸
ADAM19 ▸ VASP ▸ MRXS5 ▸ MEFV ▸ SFXN1 ▸ TNFRSF1B ▸ TRAF2 ▸
CAPN15 ▸ CAPN5 ▸ C3 ▸ HCG25 ▸ CPB2 ▸ ACKR3 ▸ TSC22D3 ▸
APOA2 ▸ GRB14 ▸ PITX1 ▸ CTGF ▸ GH1 ▸ TNP2 ▸ MAP2K5 ▸
ATP8A2 ▸ FCGR2B ▸ CTSB ▸ HCG24 ▸ HCG21 ▸ MYO19 ▸ BCL6 ▸
HCG8 ▸ CAPN14 ▸ HCG23 ▸ CD163 ▸ CXCR6 ▸ CYP1A2 ▸ CP ▸
NFKBIZ ▸ ARSA ▸ HCG11 ▸ CCL5 ▸ CXCL3 ▸ FUT1 ▸ PAK7 ▸
DNASE2 ▸ CPB1 ▸ VAV1 ▸ FOXO6 ▸ F2RL2 ▸ VDR ▸ FUT11 ▸
MYO16 ▸ CAPN11 ▸ CXCL5 ▸ WNT2 ▸ NPY ▸ SPP2 ▸ SMAD1 ▸
FOXO4 ▸ CAPN1 ▸ SLPI ▸ DDX58 ▸ THBD ▸ PTPN22 ▸ UCN2 ▸
HCG15 ▸ CSH2 ▸ ADAM10 ▸ TNP1 ▸ ALOX5 ▸ POU2F1 ▸ NPY6R ▸
PDCD4 ▸ FUT8 ▸ JAK1 ▸ GRM8 ▸ HTR1E ▸ HTR1F ▸ GALR3 ▸
TAS2R38 ▸ INSL5 ▸ S1PR1 ▸ TAS2R50 ▸ TAS2R41 ▸ ADRA2C ▸ HTR1B ▸
MTNR1B ▸ CCR7 ▸ PENK ▸ TAS2R45 ▸ ADORA1 ▸ XCR1 ▸ PPY ▸
TAS2R5 ▸ MCHR2 ▸ TAS2R42 ▸ SSTR1 ▸ LPAR5 ▸ TAS2R46 ▸ TAS2R19 ▸
TAS2R43 ▸ NPBWR1 ▸ S1PR2 ▸ BDKRB2 ▸ GNAI3 ▸ CCR6 ▸ PNOC ▸
HTR1A ▸ HTR5A ▸ HCAR2 ▸ TAS2R1 ▸ OPRL1 ▸ SSTR4 ▸ DRD4 ▸
CCR8 ▸ KNG1 ▸ NPY1R ▸ HRH4 ▸ CCL19 ▸ GNAI1 ▸ HEBP1 ▸
PDYN ▸ RXFP4 ▸ GNAI2 ▸ NMUR2 ▸ TAS2R8 ▸ DRD3 ▸ C5AR1 ▸
CCL25 ▸ TAS2R40 ▸ TAS2R14 ▸ CCL27 ▸ TAS2R7 ▸ DRD2 ▸ GPER1 ▸
GRM4 ▸ GRM3 ▸ S1PR4 ▸ NPB ▸ DARC ▸ ADRA2B ▸ OXGR1 ▸
TAS2R39 ▸ TAS2R4 ▸ HRH3 ▸ TAS2R3 ▸ GABBR2 ▸ CCR10 ▸ SSTR5 ▸
P2RY4 ▸ GRM2 ▸ GNG2 ▸ CCL16 ▸ SUCNR1 ▸ CCR4 ▸ CCR1 ▸
GALR1 ▸ APLNR ▸ OPRK1 ▸ NMU ▸ FPR1 ▸ MTNR1A ▸ S1PR3 ▸
FPR3 ▸ GNB1 ▸ ADORA3 ▸ NPY5R ▸ CCR2 ▸ SSTR3 ▸ TAS2R9 ▸
CHRM2 ▸ CHRM4 ▸ CCL28 ▸ HCAR3 ▸ S1PR5 ▸ TAS2R10 ▸ PPBP ▸
TAS2R16 ▸ CX3CR1 ▸ RXFP3 ▸ GNAT3 ▸ P2RY13 ▸ OXER1 ▸ GRM7 ▸
HTR1D ▸ SSTR2 ▸ C3AR1 ▸ TAS2R13 ▸ CCR9 ▸ U2AF1 ▸ HCAR1 ▸
NPBWR2 ▸ NMUR1 ▸ BDKRB1 ▸ TAS2R31 ▸ TAS2R20 ▸ PMCH ▸ PTGER3 ▸
MT-RNR2 ▸ MCHR1 ▸ GRM6 ▸ P2RY12 ▸ OPRD1 ▸ GALR2 ▸ PYY ▸
PTGDR2 ▸ ANXA1 ▸ ADRA2A ▸ NPY2R ▸ TAS2R30 ▸ TAS2R60 ▸ GABBR1 ▸
Data information
Please see the Gene Interactions Track Manual.