◀ Back to MAPK7
GJC1 — MAPK7
Text-mined interactions from Literome
Hossain et al., J Cell Physiol 1999
:
Since many of these agents activate additional protein kinases, our present study examined whether activation of
MAPK was
sufficient for Cx43 phosphorylation and
GJC blockade ... Taken together, our results suggest that disruption of
GJC is not solely
mediated by either activated
MAPK or Cx43 phosphorylation but requires the participation of additional kinases and regulatory components
Lin et al., J Cell Biol 2001
:
Furthermore, we did not find evidence for a
role for
mitogen activated protein kinase in mediating the disruption of
GJC by v-Src
Lin et al., Cell communication & adhesion 2006
(Cell Transformation, Neoplastic) :
Cells coexpressing v-Src and the triple serine to alanine mutant, Cx43S255/279/282A, confirmed that
mitogen activated protein ( MAP ) kinase phosphorylation of Cx43 was not
required for v-Src induced disruption of
GJC and that tyrosine phosphorylation was sufficient
Abdelmohsen et al., Biochem Biophys Res Commun 2007
:
Thus, EGF- or menadione induced loss of
GJC is
mediated by ERK-1/2 but not
ERK-5 in rat liver epithelial cells