Gene interactions and pathways from curated databases and text-mining

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IL6 — THBD

Text-mined interactions from Literome

Archipoff et al., Biochem J 1991 : Heterogeneous regulation of constitutive thrombomodulin or inducible tissue-factor activities on the surface of human saphenous-vein endothelial cells in culture following stimulation by interleukin-1 , tumour necrosis factor, thrombin or phorbol ester
Hirokawa et al., J Biochem 1990 : Previous studies have shown that thrombomodulin (TM) on endothelial cells is down-regulated by endotoxin, interleukin-1 beta (IL-1 beta), and tumor necrosis factor (TNF)
Smadja et al., Pediatr Cardiol 2010 (Heart Defects, Congenital...) : The study investigated soluble markers of endothelial damage or activation ( thrombomodulin , soluble endothelial protein C receptor, and soluble E-selectin ), inflammation ( interleukin-6 ), and angiogenic cytokine levels [ vascular endothelial growth factor ( VEGF ) and placental growth factor (PlGF) ] in 26 patients with CHD, 16 with reversible PAH ( median age, 2 years ) and 10 with irreversible PAH ( median age, 9 years )