Gene interactions and pathways from curated databases and text-mining

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FGF2 — IGFBP5

Text-mined interactions from Literome

De Los Rios et al., J Cell Physiol 2000 : Neither growth hormone (GH), fibroblast growth factor-2 , nor thyroxine ( T ( 4 ) ) had any effect on IGFBP expression or release
Chamberlain et al., Mol Cell Endocrinol 2001 : In Experiment 2A, insulin stimulated production of IGFBP-5 by thecal cells, and basic fibroblast growth factor (bFGF) inhibited the insulin induced increase in IGFBP-5 production ; epidermal growth factor (EGF) and luteinizing hormone were without effect
Pons et al., Endocrinology 1992 : While IGFBP levels in neuronal cultures were greatly increased by bFGF , their production by glial cells was inhibited
Canalis et al., J Biol Chem 1995 : In conclusion, bFGF , TGF beta 1, and PDGF BB inhibit IGFBP-5 expression in Ob cells independently of their mitogenic activity and through mechanisms that involve decreased transcription
Kummer et al., Endocrinology 1996 : The stimulatory effect of bFGF and IGF-I on IGFBP production was apparent after a 2- to 3-day exposure of the mesencephalic cultures to the peptides