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FGF2 — IGFBP5
Text-mined interactions from Literome
De Los Rios et al., J Cell Physiol 2000
:
Neither growth hormone (GH),
fibroblast growth factor-2 , nor thyroxine ( T ( 4 ) )
had any effect on
IGFBP expression or release
Chamberlain et al., Mol Cell Endocrinol 2001
:
In Experiment 2A, insulin stimulated production of
IGFBP-5 by thecal cells, and
basic fibroblast growth factor (bFGF) inhibited the insulin induced increase in IGFBP-5 production ; epidermal growth factor (EGF) and luteinizing hormone were without effect
Pons et al., Endocrinology 1992
:
While
IGFBP levels in neuronal cultures were greatly
increased by
bFGF , their production by glial cells was inhibited
Canalis et al., J Biol Chem 1995
:
In conclusion,
bFGF , TGF beta 1, and PDGF BB
inhibit IGFBP-5 expression in Ob cells independently of their mitogenic activity and through mechanisms that involve decreased transcription
Kummer et al., Endocrinology 1996
:
The stimulatory
effect of
bFGF and IGF-I on
IGFBP production was apparent after a 2- to 3-day exposure of the mesencephalic cultures to the peptides