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IL3 — RAF1
Text-mined interactions from Literome
Sutor et al., J Biol Chem 1999
:
Furthermore, agents that elevated cAMP suppressed
IL-3 induced
c-Raf activation but did not inhibit MEK activation ... Taken together, these results suggest that
IL-3 receptors engage and
activate both
c-Raf and A-Raf in hemopoietic cells
Carroll et al., J Biol Chem 1990
:
Interleukin-3 and granulocyte-macrophage colony stimulating factor
mediate rapid phosphorylation and activation of cytosolic
c-raf ...
Interleukin-3 (IL-3) and granulocyte-macrophage colony stimulating factor
induce the rapid phosphorylation of the
c-raf protein in the growth factor dependent FDC-P1 and DA-3 murine myeloid cell lines ...
IL-3 and granulocyte-macrophage colony stimulating factor
induce phosphorylation of
c-raf at both serine and tyrosine residues
Kanakura et al., Blood 1991
:
Granulocyte-macrophage colony stimulating factor and
interleukin-3 induce rapid phosphorylation and activation of the proto-oncogene
Raf-1 in a human factor dependent myeloid cell line ... GM-CSF and
IL-3 rapidly and transiently
increased Raf-1 kinase activity using Histone H1 as a substrate in an immune complex kinase assay in vitro
Terada et al., J Biol Chem 1995
:
Induction of the dominant negative Ras ( S17N ) effectively inhibited the
IL-3 induced
activation of
c-Raf-1 and mitogen activated protein kinase ( MAPK )