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EIF2AK2 — SP1
Text-mined interactions from Literome
Ward et al., Virology 2003
:
These results, taken together, strongly suggest a
role for
Sp1 in basal and Sp3 in inducible transcription of
PKR and that a potential function of the KCS element is to facilitate the recruitment of ISGF-3 complex components to the PKR promoter to stimulate transcription
Das et al., J Biol Chem 2006
:
Overexpression of
Sp1 in human U cells
resulted in increased
PKR promoter activity ... In Drosophila SL2 cells lacking Sp proteins, both
Sp1 and Sp3 large but not small isoforms
activated PKR promoter expression, with the Sp1 mediated activation dominant