Gene interactions and pathways from curated databases and text-mining

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EIF2AK2 — SP1

Text-mined interactions from Literome

Ward et al., Virology 2003 : These results, taken together, strongly suggest a role for Sp1 in basal and Sp3 in inducible transcription of PKR and that a potential function of the KCS element is to facilitate the recruitment of ISGF-3 complex components to the PKR promoter to stimulate transcription
Das et al., J Biol Chem 2006 : Overexpression of Sp1 in human U cells resulted in increased PKR promoter activity ... In Drosophila SL2 cells lacking Sp proteins, both Sp1 and Sp3 large but not small isoforms activated PKR promoter expression, with the Sp1 mediated activation dominant