Gene interactions and pathways from curated databases and text-mining

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IRF6 — SEC14L2

Text-mined interactions from Literome

Klein-Patel et al., Toxicological sciences : an official journal of the Society of Toxicology 2006 : As little as 2.5 microg/cm ( 2 ) of ROFA inhibited LPS induced TAP gene expression by 30 % ... SiO ( 2 ) and TiO ( 2 ) were utilized as controls and did not inhibit LPS induction of TAP gene expression in BTE
Al-Haddawi et al., Vet Immunol Immunopathol 2007 (Bovine Virus Diarrhea-Mucosal Disease...) : These data indicate that infection with a type 2 BVDV isolate inhibits the LPS induced upregulation of TAP mRNA expression and lactoferrin secretion by tracheal epithelial cells, suggesting a novel mechanism by which this virus abrogates respiratory innate immune responses and predisposes to bacterial pneumonia in cattle
Hirata et al., Biol Pharm Bull 2010 : Tip associated protein (TAP) , a key molecule in the nucleocytoplasmic transport of TNFalpha mRNA, was up-regulated by LPS , but this increase was impaired by the Tpl2 inhibitor