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MMP9 — NCAM2
Text-mined interactions from Literome
Shichi et al., J Pharmacol Exp Ther 2011
(Brain Ischemia...) :
MMP inhibition or MMP-9 gene KO
attenuated the infarction, behavioral abnormalities, and decrease of
NCAM ( 180 kDa ) observed after MCAO in mice ... The present findings clearly suggest that
MMP-2/MMP-9 mediated
NCAM proteolysis is implicated in the exacerbation of ischemic neuronal damage
Fujita-Hamabe et al., Biol Pharm Bull 2012
:
We conclude that oxidative stress can
induce cleavage of
NCAM-180 through up-regulation of
MMP-9 during the early phase of oxidative stress
Edvardsen et al., Proc Natl Acad Sci U S A 1993
(Glioma) :
We report here that the expression of transmembrane
NCAM-B , but not of glycosyl-phosphatidylinositol linked NCAM-C,
induces a down-regulation of
92-kDa gelatinase ( matrix metalloproteinase 9 ) and interstitial collagenase ( matrix metalloproteinase 1 ), indicating that cellular expression of the recognition molecule NCAM regulates the metabolism of the surrounding matrix