Gene interactions and pathways from curated databases and text-mining

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MMP9 — ROCK2

Text-mined interactions from Literome

Xue et al., Hepatology research : the official journal of the Japan Society of Hepatology 2008 : Our aim was to test the anticancer effects of Rho/ROCK inhibitor, Y-27632, including possible mechanisms in a highly metastasizing hepatocellular carcinoma ( HCC ) mouse model on its secretion of matrix metalloproteinase ( MMP ) and tumor progression
Ye et al., Oncogene 2010 (Bone Cysts, Aneurysmal) : TRE17 induces transcription of MMP-9 through activation of nuclear factor-kappaB (NF-kappaB), mediated in part by the GTPase RhoA and its effector kinase, ROCK
Matsuoka et al., Clin Exp Metastasis 2011 (Adenocarcinoma, Scirrhous...) : The effect of ROCK inhibitor, Y-27632 on the mRNA expression of the integrin family and MMP in gastric carcinoma cells was subsequently examined by Reverse transcriptional ( RT ) -PCR analysis