Gene interactions and pathways from curated databases and text-mining

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ECM1 — IRF6

Text-mined interactions from Literome

Zu et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2007 (Hyperplasia) : To investigate the effects of saikosaponin-d ( SSd ) on glomerular mesangial cells (MCs) proliferation and hyperplastic extracellular matrix ( ECM ) induced by lipopolysaccharide (LPS) to provide experimental proof for its use in prevention and treatment of glomerulosclerosis
Hao et al., Zhonghua Er Ke Za Zhi 2007 : LPS could induce increased secretion of the ECM , including LN, FN, ColIV ; FOS could inhibit the secretion of ECM in GMC in a dose dependent manner at mRNA and protein levels
Heremans et al., Lymphokine Res 1989 (Disease Models, Animal...) : Studies are reviewed in which the role of IFN-gamma in different models of inflammation in mice is examined : LPS induced generalized Shwartzman reaction, experimental allergic encephalomyelitis ( EAE ) and experimental cerebral malaria ( ECM )
Wessel et al., Development 1989 : Thus, although the accumulation of many gene products occurred independently of the embryonic collagenous matrix, the accumulation of LpS1 and LvS1 appeared to be mediated by the ECM
Seid et al., Nucleic Acids Res 1997 : Disruption of the ECM by preventing collagen deposition using the lathrytic agent beta-aminopropionitrile ( BAPN ) inhibits LpS1 gene transcription