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MTA1 — WNT1

Text-mined interactions from Literome

Kumar et al., Cancer Res 2010 (Breast Neoplasms...) : Furthermore, downregulation of beta-catenin in cells with elevated MTA1s level was accompanied by a corresponding decrease in the expression of Wnt1 target genes, establishing a mechanistic role for the ERK/glycogen synthase kinase 3beta/beta-catenin pathway in the stimulation of the Wnt1 target genes by MTA1s in mammary epithelial cells
Yan et al., J Biol Chem 2012 (Breast Neoplasms...) : We also discovered that leptin increases the expression of an important modifier of Wnt1 signaling, MTA1, which is integral to leptin mediated regulation of the Wnt/ß-catenin pathway as silencing of MTA1 inhibits leptin induced Wnt1 expression, GSK3ß phosphorylation, and ß-catenin activation