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PLCG1 — RAC2

Text-mined interactions from Literome

Piechulek et al., J Biol Chem 2005 : PLCgamma(2), but not PLCgamma(1) , was markedly activated in intact cells by constitutively active Rac1 ( G12V ), Rac2 ( G12V ), and Rac3 ( G12V ) but not by Cdc42 ( G12V ) and RhoA ( G14V )
Choi et al., Cell Signal 2007 : Interestingly, PLC-gamma1 potentiated the activations of Rac , thus integrin induced lamellipodia formation was up-regulated
Sala et al., Cancer Res 2008 (Breast Neoplasms...) : In this study, we show that down-regulation of PLCgamma1 expression severely impairs activation of the small GTP binding protein Rac and cell invasion in breast cancer cell lines and U87 in vitro