Gene interactions and pathways from curated databases and text-mining

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ESR1 — GRM1

Text-mined interactions from Literome

Boulware et al., J Neurosci 2005 : Activation of estrogen receptor alpha (ERalpha) led to mGluR1a signaling, triggering CREB phosphorylation through phospholipase C regulation of MAPK
Boulware et al., J Neurosci 2007 : ER alpha activation of mGluR1a is dependent on CAV1, whereas CAV3 is necessary for ER alpha and ER beta activation of mGluR2/3