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EIF4EBP1 — LEP
Text-mined interactions from Literome
Maya-Monteiro et al., J Biol Chem 2008
(Inflammation) :
Leptin induces phosphorylation of p70 ( S6K ) and
4EBP1 key downstream signaling intermediates of the mammalian target of rapamycin (mTOR) pathway in a rapamycin-sensitive mechanism
Pérez-Pérez et al., Biol Reprod 2009
:
We have found that
leptin dose-dependently
stimulates the phosphorylation and activation of the translation initiation factor EIF4E as well as the phosphorylation of the EIF4E binding protein
EIF4EBP1 ( PHAS-I ), which releases EIF4E to form active complexes