Gene interactions and pathways from curated databases and text-mining

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EIF4EBP1 — LEP

Text-mined interactions from Literome

Maya-Monteiro et al., J Biol Chem 2008 (Inflammation) : Leptin induces phosphorylation of p70 ( S6K ) and 4EBP1 key downstream signaling intermediates of the mammalian target of rapamycin (mTOR) pathway in a rapamycin-sensitive mechanism
Pérez-Pérez et al., Biol Reprod 2009 : We have found that leptin dose-dependently stimulates the phosphorylation and activation of the translation initiation factor EIF4E as well as the phosphorylation of the EIF4E binding protein EIF4EBP1 ( PHAS-I ), which releases EIF4E to form active complexes