Gene interactions and pathways from curated databases and text-mining

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ACACA — NAMPT

Text-mined interactions from Literome

Bowlby et al., PloS one 2012 : Nampt blockade resulted in reduced ATP levels and concomitant activation of AMP activated protein kinase (AMPK) and phosphorylation of acetyl-CoA carboxylase (ACC)
Garg et al., Endocrinology 2013 (Glucose Intolerance) : Liver glucose transporter (Glut) 1 and DNL increased with decreased hepatic acetyl-CoA carboxylase (ACC) and fatty acid synthase but increased WAT fatty acid transport protein-1 and peroxisomal proliferator activated receptor-?, resistin, and visfatin gene expression