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MMP2 — RHOA

Text-mined interactions from Literome

Do et al., Mol Cancer Res 2007 (Ovarian Neoplasms) : In contrast, expression of the constitutively active RhoA ( G14V ) mutant diminished LPA induced pro-MMP-2 activation
Sun et al., Clin Exp Pharmacol Physiol 2010 : 6. The results of the present study indicate that PDE5 inhibition suppresses RhoA/ROCK mediated MMP-2 production by PASMC, which may contribute to the regulation of pulmonary vascular remodelling
Chan et al., Cardiovasc Ther 2012 (Diabetes Mellitus) : Under high glucose conditions, simvastatin dose-dependently inhibited VSMC migration, decreased PI3K/Akt pathway activity, reduced c-Raf and Ras expression, increased RhoB but not RhoA , Rac1, and Cdc2 expression, dose-dependently inhibited MMP-2 , but not MMP-9, activity, and dose-dependently inhibited NF-?B activity
Serratì et al., Arthritis Rheum 2013 (Scleroderma, Systemic) : Motility increase required Rac1 activation and RhoA inhibition and was inhibited by an MMP inhibitor