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CCK — TNF
Text-mined interactions from Literome
Ling et al., World J Gastroenterol 2001
(Shock, Septic) :
In the heart,
CCK-8 significantly
inhibited LPS induced increase of
TNF-alpha ( 864 +/- 123 ng.L ( -1 ) in CCK-8+LPS group vs 1599 +/- 227 ng.L ( -1 ) in LPS group, P < 0.01 ), and IL-1beta ( 282 +/- 93 ng.L ( -1 ) in CCK-8+LPS group vs 621 +/- 145ng.L ( -1 ) in LPS group, P < 0.01 )
Meng et al., World J Gastroenterol 2002
(Endotoxemia...) :
CCK-8 inhibits expression of
TNF-alpha in the spleen of endotoxic shock rats and signal transduction mechanism of p38 MAPK ... To study the
effect of sulfated
cholecystokinin-octapeptide ( CCK-8 ) on systemic hypotension, gene and protein expression of
TNF-alpha in the spleen of lipopolysaccharide (LPS) induced endotoxic shock ( ES ) rats, and further investigate the signal transduction mechanism of p38 mitogen activated protein kinase ( MAPK )
Meng et al., Sheng Li Xue Bao 2002
(Shock, Septic) :
The results showed that CCK-8 alleviated LPS induced decrease in MAP of rats ; compared with the control, LPS elevated the levels of TNF-alpha, IL-1 beta and IL-6 in serum and lung significantly, while
CCK-8 significantly
inhibited the LPS induced increases in
TNF-alpha , IL-1 beta and IL-6 in serum and lung
Miyamoto et al., Diabetes 2012
(Diabetes Mellitus...) :
Furthermore,
CCK-8S inhibited both expression of
tumor necrosis factor-a and chemotaxis in cultured THP-1 cells