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KAT8 — TNF

Text-mined interactions from Literome

Zhou et al., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 2005 (Disease Models, Animal...) : Cytokines are the direct mediators for multiple organ failure (MOF), and MOF is triggered by TNF-alpha and a cascade of cytokine release, with a prolonged high-expression of IL-6
Matsubara et al., PloS one 2012 : Using a rat osteoclast-specific mAb, Kat1, we found that TNF-a and TGF-ß specifically increased Kat1 ( + ) c-fms ( + ) and Kat1 ( + ) c-fms ( - ) cells but not Kat1 ( - ) c-fms ( + ) cells ... The combination of TNF-a, TGF-ß, and M-CSF induced Kat1 ( + ) CD11b ( + ) cells, but these cells were also induced by TNF-a alone