Gene interactions and pathways from curated databases and text-mining

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EGF — IFNG

Text-mined interactions from Literome

Garcia-Lloret et al., J Leukoc Biol 2000 (Inflammation) : Optimal monocyte mediated syncytiotrophoblast death requires both lipopolysaccharide (LPS) and IFN-gamma and is inhibited by either anti-tumor necrosis factor (TNF) antibody or epidermal growth factor
Uribe et al., Am J Physiol Gastrointest Liver Physiol 2002 : Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells : implications for chloride secretion
Boente et al., Am J Obstet Gynecol 1992 (Ovarian Neoplasms) : Because the up-regulation of epidermal growth factor receptors by interferon gamma appears to be confined to malignant cells, interferon gamma may facilitate immunotherapy and imaging of ovarian cancers by means of immunoconjugates directed against the epidermal growth factor receptor
Valyi-Nagy et al., J Invest Dermatol 1992 : Human ( hu ) recombinant ( r ) tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma induced EGF/TGF-alpha receptor and TGF-alpha expression by keratinocytes as determined by immunohistochemistry
Burova et al., FEBS Lett 2007 : The present report provides evidence that, in A431 cells, interferon gamma (IFNgamma) induces the rapid ( within 5 min ), and reversible, tyrosine phosphorylation of the epidermal growth factor receptor (EGFR)
Karasaki et al., J Biol Chem 1989 : Pretreatment with IFN-gamma for 24 h enhanced the TPA induced inhibition of EGF binding whereas IFN-gamma alone had no effect on binding
Dignass et al., Gastroenterology 1993 : The restitution promoting cytokines TGF-alpha, EGF , IL-1 beta, and IFN-gamma increase the production of bioactive TGF-beta 1 peptide in wounded IEC-6 cell monolayer
Wang et al., In Vivo 1997 (Carcinoma, Hepatocellular) : In this study, the transmodulatory effect of IFN gamma on EGF receptor of human hepatocellular carcinoma cell line HepG2 was investigated ... However, the effect appeared only if EGF was present, but not mediated by IFN gamma alone