Vass et al., Ann Neurol 1992
(Demyelinating Diseases) :
Our data suggest that the deleterious effect of interferon-gamma on multiple sclerosis may be not only due to its effect on antigen presentation but also due to potentiation of demyelination
Lees et al., J Clin Invest 2007
(Demyelinating Diseases...) :
The exact role ( s ) of the cytokine IFN-gamma in the demyelinating disease multiple sclerosis remain controversial, with evidence suggesting both detrimental and protective effects of the cytokine in MS and MS models such as EAE