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CSF1R — IL3

Text-mined interactions from Literome

Suzuki et al., Am J Hematol 2004 : GM-CSF or IL-3 down-regulated the expression of M-CSFR ... These data demonstrate that GM-CSF and IL-3 primarily support the differentiation of monocytes into DCs and inhibit M-CSF dependent differentiation into macrophages by suppressing the expression of M-CSFR , thereby promoting differentiation into DCs
Yogesha et al., J Biol Chem 2005 : In osteoclast precursors, IL-3 and GM-CSF inhibited c-Fms expression post-transcriptionally
Gupta et al., J Immunol 2010 (Bone Resorption) : To investigate the mechanism of IL-3 action, we analyzed the effect of IL-3 on the receptor activator of NF-kappaB and c-Fms receptors and c-Fos, PU.1, NFAT cytoplasmic 1, and RelB transcription factors essential for osteoclastogenesis ... IL-3 significantly inhibited c-Fms and downregulated both PU.1 and c-Fos at both mRNA and protein level
Chen et al., J Immunol 1986 : Binding studies with radioactive labeled CSF-1 ( 125I-CSF-1 ) showed that IL 3 treatment induced an increased expression of CSF-1 receptor activity by PEM which appears to be a result of increased number of available receptor sites