Gene interactions and pathways from curated databases and text-mining

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IL4 — TRAF6

Text-mined interactions from Literome

Lomaga et al., Genes Dev 1999 (Osteopetrosis) : TRAF6 deficiency results in osteopetrosis and defective interleukin-1 , CD40, and LPS signaling
Basaki et al., Arch Biochem Biophys 2002 (Burkitt Lymphoma) : These results suggest that in DG75 cells, TRAF3 induced MEK1 activation may be involved in CD40 mediated upregulation of IL-4-driven germline C epsilon transcription
Mason et al., Infect Immun 2004 : TRAF6 dependent mitogen activated protein kinase activation differentially regulates the production of interleukin-12 by macrophages in response to Toxoplasma gondii
Frobøse et al., Mol Endocrinol 2006 : Suppressor of cytokine Signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex