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IL31 — STAT1
Text-mined interactions from Literome
Subramaniam et al., Biochem Biophys Res Commun 1999
:
Immunoprecipitation with specific antibodies followed by Western blot analysis with antiphosphotyrosine antibody has shown that in U937 cells,
interleukin-17 induces time dependent stimulation of tyrosine phosphorylation of JAK 1, 2 and 3, Tyk 2 and
STAT 1 , 2, 3 and 4 within 0.5 to 30 min. Interleukin-17 mediated tyrosine phosphorylation of these proteins strongly suggests that the JAK/STAT signaling pathway may play a major role in transducing signals from interleukin-17 receptors to the nucleus
Lee et al., J Exp Med 1999
:
Interestingly,
interleukin (IL)-7 selectively
activated STAT1 and induced MHC class I in mature T but not B cells
Dambacher et al., Gut 2007
(Cytomegalovirus Infections...) :
Interleukin 31 mediates MAP kinase and
STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease ...
IL31 mediates ERK-1/2, Akt,
STAT1 , and STAT3 activation in IEC resulting in enhanced IEC migration
Kasraie et al., Allergy 2013
:
Interleukin-31 strongly
activated STAT-1 and 5 but not STAT-3 in human macrophages after up-regulation of IL-31 receptor with staphylococcal exotoxins