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ANG — PRKAR2A

Text-mined interactions from Literome

Shimoni et al., Am J Physiol Heart Circ Physiol 2004 (Diabetes Mellitus, Experimental...) : ANG II affects multiple cellular pathways including activation of protein kinase C ( PKC ) and several tyrosine kinases as well as inhibition of protein kinase A (PKA)
Hubbard et al., Cell Immunol 2005 : Cyclic AMP dependent protein kinase (PKA) played a major role in this enhancement since the PKA inhibitor, H89, blocked secretion of Ang2
Lara et al., Arch Biochem Biophys 2010 : Cholera toxin, an activator of Gs protein, mimicked it ; ( 2 ) in the presence of Ang II, Ang- ( 1-7 ) increased the PKA activity 10-fold ; ( 3 ) the peptide inhibitor of PKA blocked the Ang- ( 1-7 ) effect on Ang II-stimulated Na+-ATPase ; ( 4 ) Ang- ( 1-7 ) reverses the Ang II-stimulated PKC activity ; ( 5 ) cAMP mimicked the Ang- ( 1-7 ) effect on the Ang II-stimulated Na+-ATPase
Saraiva et al., PloS one 2011 (Malaria, Falciparum) : These results indicate that the effect of Ang- ( 1-7 ) on P. falciparum blood stage involves a MAS mediated PKA inhibition