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ALPPL2 — CA2

Text-mined interactions from Literome

Li et al., Biol Chem 2001 : GCAP1 activates photoreceptor guanylate cyclase 1 (GC1) at low free [ Ca2+ ] ( < 50 nM, in the light ), but inhibits it at physiological high [ Ca2+ ] ( 1 microM, in the dark )
Hwang et al., Biochemistry 2002 : We applied surface plasmon resonance (SPR) spectroscopy to monitor the Ca2+ dependent binding of myristoylated and nonmyristoylated GCAP-1 and GCAP-2 to immobilized phospholipid membranes
Dizhoor et al., J Biol Chem 1996 : Unexpectedly we also found that activation of RetGCs by a Ca2+-insensitive mutant is inhibited by Ca2+ loaded wild type GCAP-2
Otto-Bruc et al., Proc Natl Acad Sci U S A 1997 : These results suggest that although GCAP1 is involved in the Ca2+-sensitive regulation of GC in rod and cone outer segments, GCAP2 may have non-phototransduction functions in photoreceptors and inner retinal neurons
Laura et al., Biochemistry 1998 : These findings suggest that GCAP-2 interacts constituitively with the KHDs of RetGC-1 and RetGC-2 and that cGMP synthesis is controlled by Ca2+ dependent conformational changes in the RetGC/GCAP complex
Hughes et al., Protein Sci 1998 : Ca2+ dependent conformational changes in bovine GCAP-2