Gene interactions and pathways from curated databases and text-mining

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CA2 — STX1A

Text-mined interactions from Literome

Ohyama et al., J Neurosci 2002 : Regulation of exocytosis through Ca2+/ATP dependent binding of autophosphorylated Ca2+/calmodulin activated protein kinase II to syntaxin 1A
Tian et al., J Biol Chem 2003 : Ca2+ dependent phosphorylation of syntaxin-1A by the death associated protein (DAP) kinase regulates its interaction with Munc18
Watanabe et al., Mol Biol Cell 2005 : Myosin-Va regulates exocytosis through the submicromolar Ca2+ dependent binding of syntaxin-1A ... Furthermore, we found that syntaxin-1A binding by myosin-Va in the presence of Ca2+ depends on the release of calmodulin from the myosin-Va neck, allowing syntaxin-1A to occupy the vacant IQ-motif
Lopez et al., FASEB J 2007 : Previous studies indicate that the process requires Rab3 dependent tethering of membranes, SNARE complex assembly, and Ca2+ mediated activation of synaptotagmin
Lynch et al., Mol Biol Cell 2007 : Synaptotagmin C2A loop 2 mediates Ca2+ dependent SNARE interactions essential for Ca2+ triggered vesicle exocytosis
Ramakrishnan et al., J Biol Chem 2009 (Deafness) : The native otoferlin C2F domain bound syntaxin 1A and SNAP-25 in a Ca2+ dependent manner ( with optimal 61 microm free Ca2+ required for binding )
Sokolovski et al., Mol Plant 2008 (Ion Channel Gating) : Here, we report one mode of action for the SNARE mediated directly through alterations in Ca2+ channel gating and its consequent effects on cytosolic-free [ Ca2+ ] ( [ Ca2+ ] i ) elevation
Nagamatsu et al., Biochem Biophys Res Commun 1997 : In order to clarify the effect of overexpressed syntaxin 1A on glucose metabolism and intracellular Ca2+ we analyzed the glucose transport system, glucose phosphorylation activity, and cytosolic concentration of free Ca2+ ( [ Ca2+ ] i )