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EDN1 — NOS2

Text-mined interactions from Literome

Marsen et al., Pflugers Arch 1999 : Tyrosine-kinase dependent regulation of the nitric oxide synthase gene by endothelin-1 in human endothelial cells
Barton et al., J Am Soc Nephrol 2000 (Glomerulosclerosis, Focal Segmental...) : Dysfunctional renal nitric oxide synthase as a determinant of salt-sensitive hypertension : mechanisms of renal artery endothelial dysfunction and role of endothelin for vascular hypertrophy and Glomerulosclerosis
Schwerte et al., J Exp Biol 2002 : We used novel digital contrasting methods to measure the effects of endothelin-1 ( ET-1, 10 ( -6 ) to 10 ( -8 ) mol l ( -1 ) ), the nitric-oxide releasing agent sodium nitroprusside ( SNP, 10 ( -2 ) mol l ( -1 ) ) and N ( omega ) -nitro-L-arginine methyl ester hydrochloride ( L-NAME, 10 ( -4 ) mol l ( -1 ) ), a non-selective inhibitor of nitric oxide synthase , on the diameter of tiny arteries and veins of the head in anaesthetized Xenopus laevis tadpoles ( stage NF 50-53 )
Mérial-Kieny et al., Br J Pharmacol 2003 : Endothelin-1 inhibits TNF alpha induced iNOS expression in 3T3-F442A adipocytes
Liu et al., J Biol Chem 2003 : Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein jinase B/Akt
Luo et al., Am J Physiol Gastrointest Liver Physiol 2004 (Hepatopulmonary Syndrome...) : Both increased hepatic endothelin-1 (ET-1) production and pulmonary vascular ET ( B ) receptor expression with stimulation of endothelial nitric oxide synthase and TNF-alpha mediated inducible nitric oxide synthase and heme oxygenase-1 expression in pulmonary intravascular macrophages occur
Zhang et al., Acta Pharmacol Sin 2005 (Hypertension, Pulmonary) : In the PAH group, the endothelin-1 (ET-1) in serum and lungs was dramatically increased by 54 % ( 79.9 pg/mL, P < 0.01 ) and 93 % ( 166.2 pg/mL, P < 0.01 ), and mRNA levels of preproET-1, eNOS, and iNOS also increased dramatically compared with control
Ohlstein et al., J Neurosurg 1992 : An l-arginine analog inhibitor of nitric oxide synthase , L-NG-monomethyl arginine ( L-NMMA, 200 microM ), did not significantly affect basal immunoreactive endothelin levels
Keller et al., Shock 2006 (Disease Models, Animal...) : Inhibition of endothelin-1 mediated up-regulation of iNOS by bosentan ameliorates endotoxin induced liver injury in cirrhosis
Novella et al., Eur J Cardiothorac Surg 2007 (Cardiovascular Diseases) : No change in the AVP response was produced by endothelium removal, exposure to the NO precursor ( 3 x 10 ( -4 ) M L-arginine ), inhibition of nitric oxide ( NO ) synthase ( 3 x 10 ( -5 ) M L-NAME ) or soluble guanylate cyclase ( 3 x 10 ( -6 ) M 1H- [ 1,2,4 ] oxadiazol [ 4,3,-alpha ] quinoxalin-1-one ( ODQ ) ), removal of the superoxide anion ( 100 U/ml superoxide dismutase ( SOD ) plus 1200 U/ml catalase ) or hydroxyl radical ( 10 ( -4 ) M deferoxamine ), or specific alpha1 - ( 10 ( -6 ) M prazosin ) or endothelin ( 10 ( -5 ) M bosentan ) receptor antagonism
Chin et al., J Periodontal Res 2009 (Mouth, Edentulous) : The roles of the endothelin receptors A and B ( ET ( A ) and ET ( B ) ) in CsA enhanced expression of PCNA and iNOS were examined in cultured human gingival fibroblasts pretreated with receptor antagonists, by immunocytochemistry and RT-PCR, respectively
Kwok et al., Am J Physiol Gastrointest Liver Physiol 2009 : Caveolin-1 mediates endotoxin inhibition of endothelin-1 induced endothelial nitric oxide synthase activity in liver sinusoidal endothelial cells
Fujita et al., Eur J Pharmacol 1995 (Disease Models, Animal...) : We examined the effect of long-term nitric oxide ( NO ) synthase inhibition on vascular and renal endothelin-1 levels and evaluated the antihypertensive effect of endothelin ETA receptor antagonist FR139317 ( ( R ) 2 ( - ) [ ( R ) -2 ( - ) [ ( S ) -2 ( - ) [ [ 1- ( hexahydro-1H-azepinyl ) ] - carbonyl ] amino-4-methyl-pentanoyl ] amino-3 ( - ) [ 3- ( 1-methyl-1H- indolyl ) ] propionyl ] amino-3- ( 2-pyridyl ) proprionic acid ] on rats in which NO synthase was blocked
Beck et al., Kidney Int 1995 : Endothelin-1 inhibits cytokine stimulated transcription of inducible nitric oxide synthase in glomerular mesangial cells
Edwards et al., Am J Obstet Gynecol 1996 (Body Weight...) : We postulated that long-term nitric oxide synthase inhibition with L-nitro-arginine methyl ester would induce sustained hypertension, a rise in plasma levels of endothelin-1 , and fetal growth restriction ... Long-term nitric oxide synthase blockade causes sustained hypertension, elevated levels of endothelin-1 , and fetal growth restriction
Beck et al., FEBS Lett 1996 : We have recently reported that endothelin-1 completely blocks cytokine induced iNOS expression at the transcriptional level
Hirahashi et al., Pharmacology 1996 : Endothelin-1 inhibits induction of nitric oxide synthase and GTP cyclohydrolase I in rat mesangial cells
Oda et al., Eur J Pharmacol 1997 : We found that in glial cell cultures lipopolysaccharide stimulated inducible NO synthase expression and nitrite accumulation were synergistically enhanced by pretreatment with endothelin, whereas endothelin itself did not induce these responses
Lin et al., Eur J Endocrinol 1998 : Role of nitric oxide synthase in release of endothelin from cultured human endometrial cells
Murayama et al., Life Sci 1998 : Regulation of inducible NO synthase expression by endothelin in primary cultured glial cells
Gude et al., Clin Exp Pharmacol Physiol 1998 : 2. Vasoconstriction responses to 5-hydroxytryptamine ( 5-HT ) were potentiated in the presence of endothelin-1 (ET-1) , the thromboxane A2-mimetic U46619 and a nitric oxide synthase inhibitor , N-nitro-L-arginine ( NOLA ), but not in the presence of angiotensin II