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AGTR2 — PTGS2

Text-mined interactions from Literome

Hayashi et al., Prostaglandins Other Lipid Mediat 2003 : Cyclooxygenase (COX)-2 mRNA expression increased ( P < 0.05 ) at 2 and 24 h after treatment with Estrumate
Kunz et al., J Cereb Blood Flow Metab 2007 (Ischemic Attack, Transient) : The COX-2 inhibitor NS398 ( 10 mg/kg ) attenuated the production of COX-2 derived prostaglandin E ( 2 ) and reduced brain injury, but did not affect ROS production at 2 and 72 h
Zhang et al., Proc Natl Acad Sci U S A 2006 : In summary, these results demonstrate that macula densa COX-2 expression is oppositely regulated by AT(1) and AT(2) receptors and suggest that AT(2) receptor mediated cortical COX-2 elevation may mediate physiologic effects that modulate AT(1) mediated responses
Mangat et al., J Clin Invest 1997 (Hypercalcemia) : To determine if AT1 angiotensin II receptor activation was involved in the stimulation of cPLA2 and PGHS-2 in hypercalcemia, we treated rats with the AT1 receptor antagonist, losartan