Rump et al., Arch Int Pharmacodyn Ther 1978
(Organophosphate Poisoning...) :
It was shown that pro-2-PAM significantly increased activity of DFP inhibited acetylcholinesterase in the brain, quickly ceased the DFP induced paralysis of respiration, partially normalized the DFP induced abnormalities in electrocorticogram and increased the convulsive dosis of DFP
Kenley et al., Pharmacol Biochem Behav 1982
:
Effects of PAM , proPAM, and DFP on behavior, thermoregulation, and brain AChE in rats