Gene interactions and pathways from curated databases and text-mining

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MAP3K3 — MAPK10

Text-mined interactions from Literome

Deacon et al., J Biol Chem 1999 : We have examined the regulation by MEKK3 of MAPK kinase 7 ( MKK7 ) and MKK6, two novel MAPK kinases specific for JNK and p38, respectively
Korchnak et al., Cell Signal 2009 : Mixed lineage kinase 3 (MLK3) is a mitogen activated protein kinase kinase kinase ( MAP3K ) that activates multiple mitogen activated protein kinase ( MAPK ) pathways in response to growth factors, stresses and the pro-inflammatory cytokine, tumor necrosis factor (TNF)
Wang et al., J Immunol 2011 (MAP Kinase Signaling System) : Furthermore, the IL-12/IL-18-driven IFN-? production and MAPK activation in Mekk3-deficient T cells was not affected suggesting that MEKK3 may selectively mediate the TCR induced MAPK signals for IFN-? production